John F Kokai-Kun Selected Research

SYN-004

10/2018	Characterization of Clostridium difficile isolates collected during a phase 2b clinical study with SYN-004 (ribaxamase) for the prevention of C. difficile infection.
9/2016	Tolerability and Pharmacokinetics of SYN-004, an Orally Administered β-Lactamase for the Prevention of Clostridium difficile-Associated Disease and Antibiotic-Associated Diarrhea, in Two Phase 1 Studies.

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John F Kokai-Kun Research Topics

Disease

11	Infections 01/2019 - 01/2002
4	Clostridium Infections 01/2019 - 01/2016
4	Coinfection 01/2017 - 02/2007
3	Diarrhea 01/2017 - 01/2016
3	Staphylococcal Infections 07/2009 - 02/2007
2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2020 - 01/2019
2	Sepsis (Septicemia) 08/2011 - 07/2009
1	COVID-19 01/2021
1	Pneumonia (Pneumonitis) 01/2019
1	Birth Weight (Birth Weights) 08/2011
1	Body Weight (Weight, Body) 07/2009
1	Hypothermia 11/2007
1	Bacteremia 11/2007
1	Cross Infection (Nosocomial Infection) 03/2004

Drug/Important Bio-Agent (IBA)

6	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 11/2003
4	LysostaphinIBA 07/2009 - 08/2005
2	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 01/2020 - 01/2019
2	SYN-004IBA 10/2018 - 09/2016
2	Monoclonal AntibodiesIBA 08/2011 - 07/2009
2	pagibaximabIBA 08/2011 - 07/2009
1	VaccinesIBA 01/2021
1	LactamsIBA 01/2019
1	P 11 (P-11)IBA 08/2011
1	Messenger RNA (mRNA)IBA 11/2007
1	Interleukin-6 (Interleukin 6)IBA 11/2007
1	CytokinesIBA 11/2007
1	Interleukin-10 (Interleukin 10)IBA 11/2007
1	Fatty Acids (Saturated Fatty Acids)IBA 05/2007
1	beta Lactam AntibioticsIBA 02/2007
1	Oxygen (Dioxygen)IBA 02/2007
1	Teichoic AcidsIBA 03/2004
1	Streptomycin (Streptomycin Sulfate)FDA Link 01/2002

Therapy/Procedure

1	Aftercare (After-Treatment) 01/2019
1	Catheters 07/2009
1	Therapeutics 02/2007